Quinoxalines. XXIV. : Reaction of 2-Chloroquinoxaline with C-Nucleophiles
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C-F bond cleavage by intramolecular S(N)2 reaction of alkyl fluorides with O- and N-nucleophiles.
The nucleophilic substitution of alkyl fluorides was achieved in the intramolecular reactions with O- and N-nucleophiles. The intramolecular defluorinative cyclization reaction was influenced by the nature of nucleophiles, the size of the ring to be formed, and the comformational rigidity of the precursors. Intermolecular nucleophilic substitution reactions of alkyl fluorides under similar reac...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1988
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.108.6_586